Dr. Bill Cortner and his fiancée, Jan Compton, are driving to his lab when they get into a horrible car accident. Compton is decapitated. But Cortner is not fazed by this seemingly insurmountable hurdle. His expertise is in transplants, and he is excited to perform the first head transplant. Keeping Compton's head alive in his lab, Cortner plans the groundbreaking yet unorthodox surgery. First, however, he needs a body.

The life of a young, Japanese schoolgirl is destroyed when her family is killed by a Ninja-Yakuza family. Her hand cut off, she replaces it with various machines-of-death, and seeks revenge.

A kindly English botanist and a gruff American promoter lead an expedition to the Himalayas in search of the legendary Yeti.

A priest-doctor chasing a man with supernatural regenerative abilities, who has recently escaped from a medical lab, reaches a small town where the mutant goes on a killing spree.