Cute and perky college student Alice is invited to a "pool party" by Freida, a female teacher who is actually a lesbian and has designs on Alice. At the party Alice gets drunk, takes acid and immediately becomes a lesbian, taking a bath with Freida. Later Alice gets mixed up with LSD-addicted hippies, rape, more lesbians, more LSD, orgies, suicide, and having sex with guys in boxers.

Mild-mannered mystery writer D. H. Mercer has become so immersed in his material that his creation, hard-boiled private eye Biff Deegan, constantly appears to him as a hallucination. Intent on getting rid of Biff, and replacing him with a more civilized detective, Mercer soon finds himself in a genuine mystery involving art fraud, murder, and a beautiful lady in peril.

At first, Dr. Sidney Schaefer feels honored and thrilled to be offered the job of the President's Analyst. But then the stress of the job and the paranoid spies that come with a sensitive government position get to him, and he runs away. Now spies from all over the world are after him, either to get him for their own side or to kill him and prevent someone else from getting him.