Hobbs has Dominic and Brian reassemble their crew to take down a team of mercenaries; Dominic unexpectedly gets sidetracked with facing his presumed deceased girlfriend, Letty.

In coastal Cornwall, England, during the early 19th Century, a young woman who's come there to visit her aunt, discovers that she's married an inkeeper who's a member of a gang of criminals who arrange shipwrecking and murder for profit.

Rookie cop, Amelia Donaghy reluctantly teams with Lincoln Rhyme – formerly the department's top homicide detective but now paralyzed as a result of a spinal injury – to catch a grisly serial killer dubbed 'The Bone Collector'. The murderer's special signature is to leave tantalizing clues based on the grim remains of his crimes.

Suburbanite Ron is spoiled, young and not overly worried about the marijuana charges leveled against him. But, after being made out to be a drug dealer, he faces a five-year jail sentence in San Quentin State Prison. Physically frail and unaccustomed to his rough surroundings, Ron is primed to fall victim to sexual predators and bullying guards – that is, until he's befriended by Earl, a veteran inmate who finds meaning in protecting the vulnerable new kid.

A convicted thief in Dartmoor prison hides the location of the stolen Bank of England printing plates inside three music boxes. When the innocent purchasers of the boxes start to be murdered, Holmes and Watson investigate.