Five years after the events of Jurassic World Dominion, covert operations expert Zora Bennett is contracted to lead a skilled team on a top-secret mission to secure genetic material from the world's three most massive dinosaurs. When Zora's operation intersects with a civilian family whose boating expedition was capsized, they all find themselves stranded on an island where they come face-to-face with a sinister, shocking discovery that's been hidden from the world for decades.

Ethan Hunt and team continue their search for the terrifying AI known as the Entity — which has infiltrated intelligence networks all over the globe — with the world's governments and a mysterious ghost from Hunt's past on their trail. Joined by new allies and armed with the means to shut the Entity down for good, Hunt is in a race against time to prevent the world as we know it from changing forever.