A dissolute scriptwriter and a dejected actor become unwittingly drawn into a labyrinthine mess when several people experience bizarre accidental deaths in their flat. Though the men didn't deliberately cause any of the incidents, they fear that they will be unfairly pegged as murderers if they relay information to the cops, and promptly set about disposing of the corpses in gruesome ways.

Guy and his sister grow up on an island. His domineering mother keeps watch over everything from the tip of a lighthouse, his eccentric father experiments in the basement laboratory. Then there are the orphans, on whose heads the adoptive parents later find puzzling wounds. Another brother and sister pair is sent to the island: the Lightball Kids, two detectives that are meant to bring light into the darkness. The brothers and sisters are all yanked into the emotional roller coaster of first love, while something cryptic comes to light in the parents' house.

Hard-boiled newspaper reporter Larry Doyle (Robert Armstrong) goes a bit too far in celebrating a work bonus and wakes up on a train bound for St. Louis with only a buck on his person. To remedy the problem, Doyle pawns the revolver he's carrying. When the gun is subsequently used in a murder, Doyle's problems only multiply. In the meantime, he's also fallen in love with a comely stranger (Maxine Doyle) he convinced to impersonate his wife.